Method of isolating taxol from Taxus baccata
نویسندگان
چکیده
منابع مشابه
Bioactivity of Lignans from Taxus baccata.
Three lignan derivatives, (-)-taxiresinol (1), (-)-3'-demethylisolariciresinol-9'-hydroxyisopropylether (2) and (-)-3-demethylisolariciresinol (3), previously isolated from the heart-wood of Taxus baccata L. (Taxaceae) were investigated for cytotoxicity against the Oncology Cell Line Panel (breast, colon, ovary, prostate, lung and a normal adult bovine aortic endothelial cell line) as well as f...
متن کاملMolecular and Morphological Characterization of a Taxol-Producing Endophytic Fungus, Gliocladium sp., from Taxus baccata
The endophytic fungal populations of different tissues of Taxus baccata grown at high altitudes in West Bengal, India were explored. These isolated fungal populations represented different genera, which were screened for taxol production using immunoassay technique. The culture AAT-TS-4(1) that produced taxol was identified as Gliocladium sp. based on its cultural, morphological characteristics...
متن کاملAnti-ulcerogenic lignans from Taxus baccata L.
Four lignan type compounds, lariciresinol, taxiresinol, isolariciresinol and 3-demethyl-iso-lariciresinol, were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through chromatographic techniques. In vivo anti-ulcerogenic potency of these compounds was investigated on ethanol-induced ulcerogenesis model in rats at two different doses, 50 and 100 mg/kg. All compounds ...
متن کاملAntifungal activity of biflavones from Taxus baccata and Ginkgo biloba.
Bilobetin and 4'''-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species. The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium o...
متن کاملThe Presence of Taxol and Related Compounds in Taxus Baccata Native to the Ukraine (Crimea), Georgia, and Southern Russia
Twenty-eight leaf and twig samples and one bark sample of Taxus baccata from the Ukraine (Crimea), Russia, and Georgia were analyzed for taxane compounds. Taxol and the related diterpenoid I 0-deacetylbaccatin III (baccatin Ill) were present in all samples and 20.7% of those samples exhibited a taxol content nearly equal to or greater than that obtained from the bark of the Pacific Yew, T. brev...
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ژورنال
عنوان ژورنال: Chemistry of Natural Compounds
سال: 1990
ISSN: 0009-3130,1573-8388
DOI: 10.1007/bf00601307